Free standard delivery over £50

Unbranded, secure packaging guaranteed

5% off your first order

When you sign up

Registered Veterinary Retailer

Genuine pet medicine

FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
From £29.30 (Incl. VAT)

FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment

From £29.30 (Incl. VAT)

FRONTLINE COMBO – Spot-On Solution

A clear amber topical solution for the control of fleas, ticks and biting lice in cats.

  • Dual-action flea and tick treatment.
  • Breaks the flea life cycle.
  • Suitable for cats and ferrets.

Order Monday to Friday before 14:00pm to guarantee next
day delivery.

Order Monday to Friday before 14:00pm to guarantee next
day delivery.

Accredited Retailer

A registered RCVS Vet Practice (7615389)

Product Features

FRONTLINE COMBO – Spot-On Solution

A clear amber topical solution for the control of fleas, ticks and biting lice in cats.

  • Dual-action flea and tick treatment.
  • Breaks the flea life cycle.
  • Suitable for cats and ferrets.

Product Details

Frontline Combo kills adult fleas and helps stop flea eggs and larvae from developing for up to six weeks after application. It also kills ticks and biting lice. This product can be used as part of a treatment plan for Flea Allergy Dermatitis (FAD), as advised by your veterinary surgeon.

  • Available in convenient multi-dose packs from a registered UK online veterinary pharmacy.

Disclaimer: For full prescribing information and safe use guidance, please refer to the product datasheet.

Instructions

Consult your vet for advice on accurate dosing and safe administration.

For detailed safety information, see the Veterinary Medicines Datasheet.

Sizes

This product is available for cats and ferrets in a convenient 6-dose pack.

Key Benefits

  • Kills Adult Fleas: Starts killing fleas within 24 hours of application.
  • Breaks the Flea Life Cycle: Contains an insect growth regulator to prevent flea eggs and larvae from developing. This is a key selling point.
  • Targets Ticks & Biting Lice: Provides effective protection against common ticks (including those that can transmit diseases) and biting lice.

Ingredients

FRONTLINE COMBO® contains fipronil and (S)–methoprene. UK: POM-V. Prescription decisions are for the person issuing the prescription alone.

Related Products

How it works to order pet prescription medications online

Choose your
treatment

Select the treatment you would like to order

Upload a prescription copy at
the checkout

Provide all the information about your pet

Express
Delivery

Your order will be sent in discreet packaging.

Frequently asked questions

How often should FRONTLINE COMBO be used?
FRONTLINE COMBO should be applied once every four weeks. Regular monthly use helps control fleas and ticks and reduces the build-up of flea eggs in the home.
Does FRONTLINE COMBO treat worms?
No. FRONTLINE COMBO only works against external parasites, such as fleas, ticks, and biting lice. It does not treat internal worms. A separate worming treatment is needed for protection against roundworms or tapeworms.
What is the difference between FRONTLINE Spot On and FRONTLINE COMBO?
FRONTLINE Spot On targets adult fleas and ticks only. FRONTLINE COMBO also helps prevent flea eggs and larvae from developing, helping prevent re-infestation in your cat and household.
Can FRONTLINE COMBO be used on kittens?
Yes. It can be used on kittens from 8 weeks of age, as long as they weigh at least 1 kg. It may also be used in pregnant and nursing cats.
Is FRONTLINE COMBO affected by water?
After 48 hours, the product will have absorbed and will not be reduced in effectiveness by water exposure. Repeated shampooing, however, may shorten how long the protection lasts.
Can I use FRONTLINE COMBO made for dogs on my cat?
No. Dog flea treatments must never be used on cats. Products made for dogs may contain ingredients or dosages that are harmful to cats. Always use a treatment clearly labelled for cats.
How do I apply FRONTLINE COMBO correctly?
Open the pipette and part the fur at the base of the neck, between the shoulder blades. Apply the contents directly onto the skin in one spot. Do not apply to the fur, as the product needs to be absorbed through the skin.

Do I need a prescription to buy POM-V pet medicines online?

Yes. POM-V items require a valid prescription from your UK vet.

 Upload your prescription during checkout. 

Photos must be clear. If details are wrong or expired, orders can’t be processed. This is standard across UK pet pharmacies.

No. Under UK law, vets must provide a written prescription if you request one for a POM-V medicine. They may charge a reasonable fee for issuing it, but they cannot refuse. This allows you to choose where to buy your pet’s medication, whether directly from your vet or from a registered UK pharmacy such as Ashcroft 4 Pets.

In the UK, most POM-V prescriptions are valid for 6 months, unless your vet specifies a shorter duration. Prescriptions for Schedule 2 or 3 controlled medicines are usually valid for 28 days and are not repeatable. At Ashcroft 4 Pets, we follow these same UK veterinary guidelines to ensure your pet’s medication is dispensed safely and legally.

At Ashcroft 4 Pets, we are a fully VMD-registered and accredited online retailer. This means every prescription and over-the-counter pet medicine we supply is safe, genuine, and dispensed according to UK law.

We follow all Veterinary Medicines Directorate (VMD) rules, and our team checks every prescription carefully before processing. You can order with confidence, knowing your pet’s health is in the hands of experts and all medicines are traceable, legally supplied, and authentic.

In the UK, most repeat prescriptions for POM-V medicines are valid for up to 6 months from the date your vet issues them. You can order multiple times within this period if your vet has authorised repeats.

For controlled medicines (Schedule 2 or 3), the prescription is valid for 28 days only and cannot be repeated. These medicines are strictly regulated due to their potential for misuse.

At Ashcroft 4 Pets, we follow UK law carefully, ensuring all prescriptions are dispensed safely, legally, and in the exact amounts prescribed.

 If your vet prescribes a human medicine for your pet under the Cascade, we can usually dispense against that prescription (with the right checks).

Latest Blogs

Dog Digestive Problems

Dog Digestive Problems: Causes & Solutions

Digestive Issues in dog Digestive problems in dogs are common and can be stressful for owners to manage. Because dogs are natural scavengers, their stomachs are often exposed to foods and substances that may upset digestion. While some stomach issues

Read More »
fake pet medication uk- Ashcroft 4 Pets

How to Spot Fake Pet Medicines in the UK

Key Takeaway Fake pet medicines pose serious health risks, but can be avoided. Always purchase treatments from VMD-authorised suppliers, verify websites carefully, and follow veterinary guidance. Being informed is the best way to protect your pet from counterfeit products. Buying

Read More »

Is Buying Pet Medicines Online Safe?

Buying pet medicines online can be safe, legal, and convenient in the UK — but only when using legitimate, regulated online pharmacies. While many pet owners turn to online pharmacies to save money, counterfeit products and fake websites have made

Read More »
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
FRONTLINE COMBO® for Cats | Flea, Tick & Lice Treatment
0